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2-CHLORORACETAMIDINE HYDROCHLORIDE

2-chloroacetamidine monohydrochloride

CAS: 10300-69-3

Molecular Formula: C2H6Cl2N2

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2-CHLORORACETAMIDINE HYDROCHLORIDE - Names and Identifiers

Name 2-chloroacetamidine monohydrochloride
Synonyms AI3-51325
2-Chloroacetamidine HCl
(1E)-2-chloroethanimidamide
CHLORACETAMIDINE HYDROCHLORIDE
2-CHLOROACETAMIDINE HYDROCHLORIDE
2-CHLORORACETAMIDINE HYDROCHLORIDE
2-CHLOROETHANIMIDAMIDE HYDROCHLORIDE
2-Chloroacetamidine monohydrochloride
2-chloroacetamidine monohydrochloride
1-amino-2-chloroethaniminium chloride
Ethanimidamide, 2-chloro-, monohydrochloride
EthaniMidaMide, 2-chloro-, Monohydrochloride
EthaniMidaMide,2-chloro-, Monohydrochloride (9CI)
CAS 10300-69-3
EINECS 233-675-7
InChI InChI=1/C2H5ClN2.ClH/c3-1-2(4)5;/h1H2,(H3,4,5);1H

2-CHLORORACETAMIDINE HYDROCHLORIDE - Physico-chemical Properties

Molecular FormulaC2H6Cl2N2
Molar Mass128.99
Melting Point98-103°C(lit.)
Boling Point146.4°C at 760 mmHg
Flash Point42.4°C
Water SolubilityInsoluble in water.
Solubility DMSO (Slightly), Methanol (Slightly)
Vapor Presure4.64mmHg at 25°C
AppearanceSolid
BRN3678354
Storage ConditionInert atmosphere,Room Temperature
StabilityHygroscopic
SensitiveMoisture Sensitive
MDLMFCD00053013

2-CHLORORACETAMIDINE HYDROCHLORIDE - Risk and Safety

Hazard SymbolsXi - Irritant
Irritant
Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
UN IDsUN3261
WGK Germany3
Hazard NoteIrritant
Hazard Class8
Packing GroupIII

2-CHLORORACETAMIDINE HYDROCHLORIDE - Introduction

Chloroacetamidine hydrochloride is an organic compound with the chemical formula C2H4ClN · HCl, which is a white crystalline solid. The following is a description of its nature, use, formulation and safety information:

Nature:
-Chloroacetamidine hydrochloride is a solid that is readily soluble in water. When dissolved in water, a dehydration reaction occurs to produce the free form of chloroacetamidine.
-Its melting point is about 138-142°C, and its boiling point is about 203°C.
-Chloroacetamidine hydrochloric acid is an acidic solution, and its acidity mainly comes from the ions of hydrochloric acid.

Use:
-Chloroacetamidine hydrochloride can be used as a reagent in organic synthesis, and is commonly used as a catalyst for acylation reactions and acylation reactions.
-It can also be used to prepare other compounds, such as amino ketones, amides, etc.

Preparation Method:
The preparation method of chloroacetamidine hydrochloric acid is generally to react chloroacetic acid with dry ammonia, and then add hydrochloric acid for neutralization reaction. Specific preparation methods can be the following:
1. Dissolve chloroacetic acid in dry ether, and then add ammonia gas to obtain chloroacetamidine. The obtained chloroacetamidine was further added to hydrochloric acid to obtain chloroacetamidine hydrochloride.
2. add chloroacetic acid to dry methanol, and then add ammonia gas to react to generate chloroacetamidine. Finally, chloroacetamidine is added to hydrochloric acid to obtain chloroacetamidine hydrochloride.

Safety Information:
-Chloroacetamidine hydrochloride is irritating and may cause irritation to the eyes, skin and respiratory tract. Therefore, wear protective glasses and gloves during use and ensure adequate ventilation.
-Avoid contact with organics, combustibles or oxidants during storage and handling to prevent fire or explosion.
-When using this compound, you should follow the safe operation procedures during use, and comply with relevant safety regulations and thinning conditions. Inappropriate operation may cause harm to the human body and the environment, so please operate under the guidance of professionals.
Last Update:2024-04-10 22:29:15
2-CHLORORACETAMIDINE HYDROCHLORIDE
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